Canine High Grade Glioma - Emerging Oncology Research

Event Details

Canine high-grade glioma is a deadly form of brain cancer that has few treatment options. It also has some very important similarities with the most common and deadliest brain cancer in people: glioblastoma. Between the limited options available for treating pet dogs and the shared features with human glioblastoma, there is much enthusiasm to study novel treatment options in pet dogs, with the hope that what is learned will benefit both species. In a clinical trial investigating immunotherapy based treatments for pet dogs with high-grade glioma, a concerning pattern emerged: French bulldogs had markedly worse survival than all other breeds, including closely related breeds. There were a variety of possible explanations for this survival disparity, and many of them have been explored. This session provides a summary of canine high-grade glioma, the methods used to investigate this survival disparity, and the results of the investigations. Listeners can also expect to gain an understanding of translational research. DISCLOSURE STATEMENTS: